This is a chance to

SEE YOU LATTR

Stop hATTR neuropathy progression.*

Start seeing results with WAINUA.

*As measured by mNIS+7 score; individual results may vary

 

WAINUA
 can prevent your neuropathy from getting worse, so you may feel stronger.

 

WAINUA can improve quality of life, allowing you to do more of the things you want to do.

Individual results may vary.

The WAINUA-treated group had a significant improvement in neuropathy impairment (mNIS+7 score) and quality of life (Norfolk QoL-DN score) after 35 weeks in a clinical trial of adults with hATTR-PN.†

†Improvement was defined as the difference between the change from baseline in the WAINUA group and a placebo group from a similar study.

WAINUA Doctor Discussion Guide

Talk to Your Healthcare Provider

Ask your healthcare provider if WAINUA is right for you. Use this Discussion Guide to prepare questions you want to ask about treatment.

Download the Discussion Guide

Safety & Side Effects

Safety - Clinical Trials

WAINUA was generally well tolerated in a clinical trial.

Vitamin A Supplementation

WAINUA suppresses the production of the protein that transports vitamin A and, therefore, vitamin A supplementation is recommended.

No Laboratory Monitoring

No additional laboratory monitoring is needed when you take WAINUA.

WAINUA may cause side effects, including:

  • Low vitamin A level, which is a serious, but common side effect of treatment with WAINUA. Your doctor should tell you to take vitamin A supplements. Do not take more than the amount of vitamin A your doctor has recommended. Call your doctor if you develop eye problems such as difficulty seeing at night or in low-lit areas (night blindness), or dry eyes. If you develop eye problems, your doctor should refer you to an eye doctor

The most common side effects include decreased vitamin A and vomiting.

These are not all the possible side effects of WAINUA. Talk to your healthcare provider about any side effects you experience.

Learn How WAINUA Can Help Stop Further hATTR-PN Progression

How WAINUA Works

Convenient, Once-Monthly Dosing that Can Work Around Your Lifestyle

How to Take WAINUA

Important Safety Information

WAINUA may cause side effects, including:

Low vitamin A level, which is a serious, but common side effect of treatment with WAINUA. Your doctor should tell you to take vitamin A supplements. Do not take more than the amount of vitamin A your doctor has recommended. Call your doctor if you develop eye problems such as difficulty seeing at night or in low-lit areas (night blindness), or dry eyes. If you develop eye problems, your doctor should refer you to an eye doctor

APPROVED USES

WAINUA injection, for subcutaneous use, 45 mg is a prescription medicine used to treat adults with polyneuropathy of hereditary transthyretin-mediated amyloidosis.

The most common side effects include decreased vitamin A and vomiting.

Before you take WAINUA, tell your healthcare provider:

  • if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. It is not known if WAINUA can harm your baby. Changes in vitamin A levels and vitamin A supplementation related to use of WAINUA may harm your unborn baby. It is not known if WAINUA passes into breast milk
  • about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take vitamin A or beta-carotene supplements

APPROVED USES

WAINUA injection, for subcutaneous use, 45 mg is a prescription medicine used to treat adults with polyneuropathy of hereditary transthyretin-mediated amyloidosis.

Please see full Prescribing Information, including Patient Information.

You may report side effects related to AstraZeneca products.

Important Safety Information

 +